When: 4:05 PM ET Watch: FOX Preview More scouting reports: Week 2
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Both of these teams lost their openers and will be eager to notch their first win of 2008. The Seahawks lost a bit of a stunner in Buffalo. Can they get back on track in Seattle, where the crowd can be a huge asset in an early-season division game?
San Francisco's home-field loss to Arizona seemed like a more profound setback than just the one game it represents in the NFC West standings. Back-to-back division losses would be a miserable way to start the season and a huge obstacle for the 49ers to overcome on the way to a postseason berth.
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