Note: ESPN's Joe Lunardi assigned a team of Bracketologists to put together Insider's Tournament Tips, offering historical analysis of the bracket and in-depth breakdowns on all 68 tournament teams to help you make smart picks.
Memphis may be under-seeded by a line or two, but the Tigers were probably happy to see relatively unathletic Saint Louis as their opening NCAA assignment. I see it the other way. The Billikens are the perfect team to frustrate and stifle the Tigers. This should be a real chess match.
Plus, you can enlist the help of Insider's Bracket Predictor tool to aid your picks.
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Take a look inside the data used by the selection committee in seeding the bracket: