Extended absence for Knowshon Moreno? 

September, 14, 2014
Sep 14
5:42
PM ET
RB Knowshon Moreno looked terrific last week, but he exited Sunday's tilt between the Miami Dolphins and Buffalo Bills early after taking a big hit. He immediately grabbed at his arm, left the game and did not return.

How bad is A.J. Green's injury? 

September, 14, 2014
Sep 14
4:53
PM ET
The Cincinnati Bengals may have won 24-10 against the Atlanta Falcons, but they lost their best player when WR A.J. Green hobbled off of the field early in the first half.

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Could Ryan Howard thrive as a DH? 

September, 14, 2014
Sep 14
1:56
PM ET
The five-year, $125 million extension that Ryan Howard signed back in April 2010 hasn't worked out well for Philadelphia, and the slugger's days in a Phillies uniform could very well be numbered. The 34-year-old first baseman has seen his production trail off considerably since signing the massive deal, but according to one scout Howard could have a bright future as a designated hitter in the American League.

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Yankees to target Nelson Cruz this winter? 

September, 14, 2014
Sep 14
1:36
PM ET
Nelson Cruz's huge season in Baltimore (.263, 39 HR, 102 RBI) is sure to make the 34-year-old slugger one of the biggest names on the free agent market this winter. Will the New York Yankees be one of his main suitors?

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How long will Morneau be out? 

September, 14, 2014
Sep 14
1:08
PM ET
Is the injury to Justin Morneau's rib cage serious enough to keep him out of the Colorado lineup for an extended period of time?

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Will Rex risk blitzing Rodgers? 

September, 14, 2014
Sep 14
12:39
PM ET
Since Aaron Rodgers arguably is the best quarterback in the NFL, opposing defenses aren't prone to test him by blitzing over and over during a game. He's too good to not get the ball out of his hands in time to hit his streaking receivers.

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Will TE Kelce's role expand soon? 

September, 14, 2014
Sep 14
11:56
AM ET
As he continues to work his way back from last year's microfracture surgery, Kansas City Chiefs TE Travis Kelce was on the field for just 18 snaps in Week 1.

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Is this finally Favors' breakout run? 

September, 14, 2014
Sep 14
11:16
AM ET
For the first three seasons of Derrick Favor's NBA career, he was all potential and no production. Last season, his fourth campaign, Favors hinted at his tremendous long-term upside at times. Will it all come together this season?

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Pettigrew stuck as a blocker this week? 

September, 14, 2014
Sep 14
10:44
AM ET
During the Detroit Lions' regular-season opener, O-linemen LaAdrian Waddle and Corey Hilliard got hurt, so Lions coaches reportedly considered using TE Brandon Pettigrew at right tackle. With Hilliard now out for the season and Waddle's status uncertain, they'll lean on rookie Cornelius Lucas and former practice-squad player Garrett Reynolds on Sunday versus the Carolina Panthers.

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Will Gay play in Sunday's final? 

September, 14, 2014
Sep 14
9:36
AM ET
During Thursday's FIBA World Cup tilt with Lithuania, Rudy Gay took a rough 'bow right to his grill. He felt it was a dirty play and got into a postgame kerfuffle with his opponents.

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What can we expect from RB Stewart? 

September, 14, 2014
Sep 14
9:06
AM ET
If you started playing fantasy football during the past couple of seasons, you may not even know who Jonathan Stewart is. Injuries limited the running back to just 15 games over the past two years, a time frame during which he averaged less than 3.7 yards per carry.

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Will ARI have Ellington, Palmer Sunday? 

September, 14, 2014
Sep 14
8:20
AM ET
The Arizona Cardinals are dealing with injuries to a pair of critically important players. RB Andre Ellington fought through his foot injury to play last week, but he was wearing a protective boot this week. QB Carson Palmer has been dealing with a nerve issue that's affecting his shoulder and kept him from practicing this week.

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Will Lattimore debut for 49ers in '14? 

September, 14, 2014
Sep 14
7:38
AM ET
The San Francisco 49ers opened the 2014 NFL campaign with just two running backs -- Frank Gore and Carlos Hyde -- on their active game-day roster. They let LaMichael James go on Monday, which leaves them with only return man Bruce Ellington as a rushing option on their roster and the injured Marcus Lattimore on the reserve/NFI list.

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Gilbert to return kicks for Cleveland? 

September, 13, 2014
Sep 13
2:47
PM ET
Rookie Cleveland cornerback Justin Gilbert has lofty expectations to live up to after being selected No. 8 overall back in May, and his Week 1 performance against Ben Roethlisberger and the rival Pittsburgh Steelers showed he still has a long ways to go. Gilbert couldn't keep up with Steelers receiver Markus Wheaton, who exposed the rookie for the key catch that set up the Steelers' game-winning field goal.

Now the question becomes how to get Gilbert up to speed.

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Will Hayden play for Raiders in 2014? 

September, 13, 2014
Sep 13
2:29
PM ET
It's been a very slow go for young cornerback D.J. Hayden since Oakland selected him in the first round of the 2013 NFL draft. He was limited to eight games as a rookie due to a sport hernia, and he's set to miss at least the first six games in 2014 due to a foot injury that led him to be placed on the physically unable to perform list.

If you also consider the serious heart issue that ended his season prematurely while at the University of Houston in 2012, Hayden's inability to stay healthy has to be a big concern for the Raiders going forward. Will he even play in 2014?

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