Mauer and Sano hit back-to-back home runs off Taijuan Walker into the bullpens behind left field for a 3-2 lead in the fourth. Sano has homered in four consecutive games.
The Twins homered three times off starter Walker (2-5).
After Byung Ho Park's walk, Juan Centeno hit a two-out double to drive in another run to extend Minnesota's lead in the fourth. A single, hit batter and walk by Walker to load the bases in the fifth inning brought his day to a close. His five earned runs marked a season high.
A solo home run by Robinson Cano gave the Mariners an early 1-0 advantage and tied Cano for the league lead in home runs with his 15th.
Grossman's solo homer off Walker evened the game at 1-1 in the second inning. Kyle Seager doubled to lead off the bottom half of the inning and scored on a wild pitch from Nolasco to take a 2-1 lead.
The Mariners reacquired slugging prospect Patrick Kivlehan from the Texas Rangers in exchange for a player to be named later or cash considerations. RHP Evan Scribner was moved to the 60-day disabled list to clear room on the 40-man roster. Kivlehan, RHP Tom Wilhemsen and OF James Jones were traded to the Rangers in exchange for OF Leonys Martin and RHP Anthony Bass in November. The Rangers had designated Kivlehan for assignment last week.
Twins: C Kurt Suzuki was not in the starting lineup but was available to play Sunday after experiencing concussion-like symptoms in Friday's game. He's still day-to-day. ... 3B Trevor Plouffe will be re-evaluated tomorrow in Oakland. He is also day-to-day after suffering a bone bruise
Mariners: SS Ketel Marte took batting practice in the cage on Sunday. He said he feels back to normal after suffering a sprained left thumb last weekend in Cincinnati. Marte is expected to play four games with Triple-A Tacoma beginning Tuesday and be activated from the disabled list on June 6.
Twins: RHP Ervin Santana (1-3, 4.17 ERA) will make his ninth start of the season against Oakland on Monday. Santana allowed a season-high six earned runs in his last start against the Kansas City Royals.